Full name

A Phase 2a, Single Dose, Open-label, Dose Exploration Study to Assess the PK-PD Activity, Safety, and Tolerability of GSK4532990 in Adult Participants With Nonalcoholic Steatohepatitis (NASH) or Suspected NASH

NCT Number
NCT06104319
Geography
US
Primary Endpoints
  • Predicted percent change from baseline in liver biopsy-derived HSD17B13 protein expression levels. Baseline (Day 1) and up to Week 16
  • Predicted percent change from baseline in liver biopsy-derived HSD17B13 mRNA expression levels. Baseline (Day 1) and up to Week 16
Order
2
Disease
Menu title
Dose Exploration Study of GSK4532990 in Participants With Nonalcoholic Steatohepatitis (NASH) or Suspected NASH (SKYLINE)
Version
Phase
2a